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SIOUX FALLS, S.D. — Sanford Health recently launched a clinical trial using a genetically engineered virus that aims to destroy therapy-resistant tumors. The Phase I immunotherapy trial is for those ages 18 and older with metastatic solid tumors that have not responded to standard treatments. The treatment injects an oncolytic (cancer-destroying) virus — vesicular stomatitis […]

Classrooms and communities in South Dakota and Massachussetts benefit from genetics ed

The Sanford Project: T-Rex Study, a Phase 2 clinical trial conducted collaboratively by Sanford Health and Caladrius Biosciences, Inc., (Caladrius)(Nasdaq: CLBS), has reached the halfway point for enrollment and treatment. The project is studying the potential of CLBS03, Caladrius’ cell therapy consisting of each patient’s own regulatory T cells, or Tregs, to help the body […]

Scientists at Sanford Research have just developed a new model which could have lasting implications for some of the world’s most dangerous diseases like cancer, diabetes, neurodegeneration, heart disease and respiratory distress syndrome. The new study, led by Peter Vitiello, Ph.D., an associate scientist in the Children’s Health Research Center at Sanford Research, was recently […]

A Sanford Research scientist studying kidney development has received $1.45 million from the National Institutes of Health to further explore how certain cells of the organ develop. Kameswaran Surendran, Ph.D., secured the award under the NIH’s National Institute of Diabetes and Digestive and Kidney Diseases. Surendran’s study will focus on understanding the underlying mechanisms that […]

Studies performed by a Sanford Research scientist using an innovative stem-cell model for a fatal developmental disorder is the focus of a recent study published in Nature Medicine. Kevin Francis, Ph.D. uncovered unique cellular defects associated with Smith-Lemli-Opitz syndrome (SLOS) by modeling this disease using induced pluripotent stem cells. Francis’ study is titled “Modeling Smith-Lemli-Opitz […]

Sanford Research scientists are published in Nature Cell Biology for their work developing a model to explore therapies for a pediatric brain tumor known as choroid plexus carcinoma. Haotian Zhao, Ph.D., is the lead author on the study titled “Sonic Hedgehog promotes proliferation of Notch-dependent monociliated choroid plexus tumour cells.” Zhao is an associate scientist […]

David Pearce, president of Sanford Research, recently talked to MED Magazine about clinical trials.

A Sanford Research scientist is using an innovative pig model to better understand a rare genetic disorder that causes tumors in the nervous system, thanks to a more than $1.7 million grant from the Children’s Tumor Foundation (CTF). Jill Weimer, Ph.D., and her team received the award as part of CTF’s Synodos for NF 1 program, a unique collaboration […]